Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides
نویسندگان
چکیده
منابع مشابه
Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides.
Second-generation anticoagulant rodenticides (SGARs) have been used since the 1980s for pest management. They are highly efficient even in warfarin-resistant rodents. Nevertheless, because of their tissue persistence, nontarget poisoning by SGARs is commonly described in wildlife. Due to this major problem, a new generation of anticoagulants must be developed to limit this risk. This study prop...
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The second-generation anticoagulants, difenacoum, bromadiolone and brodifacoum, have taken over a considerable part of the rodenticidal market during the last six to eight years. This is partly due to the higher efficiency against a larger spectrum of rodent pest species and partly to the increasing problem of physiological resistance to the older anticoagulants. Resistance of practical importa...
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Second-generation anticoagulant rodenticides were introduced to control Norway rats that had become resistant to first-generation compounds. Unfortunately, some rats have become resistant to these as well. The lack of alternative rodenticides with the same attributes of ease of use and relative safety is potentially a serious problem should resistance become so widespread that anticoagulants ar...
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From 1971 through 1997, we documented 51 cases (55 individual animals) of poisoning of non-target wildlife in New York (plus two cases in adjoining states) (USA) with anticoagulant rodenticides--all but two of these cases occurred in the last 8 yrs. Brodifacoum was implicated in 80% of the incidents. Diphacinone was identified in four cases, bromadiolone in three cases (once in combination with...
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ژورنال
عنوان ژورنال: Drug Metabolism and Disposition
سال: 2016
ISSN: 0090-9556,1521-009X
DOI: 10.1124/dmd.116.073791